Aceclofenac and paracetamol tablets offer relief for arthritis flare-ups and chronic back pain, combining an NSAID with a pain reliever. This duo is popular in Asia but increasingly recognized in Tier-1 countries like the US, UK, Canada, Australia, and the EU for managing pain and inflammation. Doctors prescribe it when single-agent therapies fall short, providing a balanced approach to symptom control without over-relying on stronger medicinces.
Primary Uses
These tablets shine in pain relief for musculoskeletal conditions. They ease arthritis-related discomfort, reducing swelling and stiffness. For back pain from strain or injury, the combination restores mobility. Post-operative pain benefits from their dual action, speeding recovery. Fever management is another key use, lowering body temperature effectively during infections or inflammation. For pain sensation reduction Gabapentin is also prescribed with it.
Studies show that Aceclofenac is effective in treating osteoarthritis and rheumatoid arthritis (NHS, UK)
What Are Aceclofenac and Paracetamol Tablets?
Aceclofenac and Paracetamol tablets combine two widely used pain-relieving medicines:
- Aceclofenac – a non-steroidal anti-inflammatory drug (NSAID) that reduces inflammation and stiffness.
- Paracetamol (Acetaminophen) – an analgesic and antipyretic that lowers fever and relieves pain.
Doctors prescribe this combination when a single medicine alone is not enough to manage pain or fever effectively. It is available in prescription form across pharmacies worldwide, including CVS (US), Walgreens (US), Boots (UK), Shoppers Drug Mart (Canada), Chemist Warehouse (Australia), Lloyds Pharmacy (EU), Apoteket (EU), and DocMorris (EU).
Mechanism of Action
Aceclofenac, an NSAID, blocks enzymes that trigger inflammation and pain. It targets cyclooxygenase, cutting prostaglandin production at injury sites. Paracetamol, or acetaminophen, acts centrally in the brain to lower pain perception and fever.
Together, they amplify effects: aceclofenac handles inflammation, paracetamol boosts analgesia. This synergy makes the combo more potent than either alone, as per pharmacokinetic studies.
Common Conditions Treated
Osteoarthritis patients in the US find it eases joint pain, improving daily function. Rheumatoid arthritis sufferers in the UK benefit from reduced swelling. Dental pain post-extraction responds well, with the duo curbing inflammation. Headaches, including tension types, get quick relief, though not ideal for chronic migraines. In Australia and Canada, it’s used for injury-related pain, supporting rehab.
Doctors often prescribe these tablets for:
- Arthritis-related pain – osteoarthritis, rheumatoid arthritis, ankylosing spondylitis
- Musculoskeletal disorders – sprains, strains, lower back pain
- Headaches & migraines (if caused by tension or inflammation)
- Dental conditions – pain after procedures
- Fever & inflammation – when other NSAIDs alone are not sufficient
Dosage & Administration
Standard tablets contain aceclofenac 100mg and paracetamol 325mg or 500mg. Adults take 1-2 tablets daily, with food to protect the stomach. Frequency depends on pain severity—up to three times a day, not exceeding 4g paracetamol daily. In the US and EU, prescriptions follow FDA or EMA guidelines, often starting at lower doses. Pharmacies like CVS in the US or Boots in the UK dispense with doctor approval.
Side Effects & Precautions
Gastric upset, nausea, or dizziness are common. Serious risks include liver damage from paracetamol overdose or GI bleeding from aceclofenac. Avoid if pregnant, with ulcers, or kidney issues. Elderly patients in Canada need monitoring for heart risks. In Australia, TGA warns of long-term use.
Drug Interactions
Alcohol heightens liver risk. Anticoagulants like warfarin increase bleeding chances. Corticosteroids amplify GI issues. Other painkillers raise overdose potential. In the EU, EMA advises checking with pharmacists like DocMorris for interactions.
Global Pharmacy Availability
In the US, CVS and Walgreens stock aceclofenac-paracetamol generics under prescription. UK’s Boots and Lloyds Pharmacy require doctor approval. Canada’s Shoppers Drug Mart dispenses for arthritis. Australia’s Chemist Warehouse offers it OTC in some forms. EU options include Apoteket in Sweden or DocMorris in Germany, following EMA rules.